In most countries the elexacaftor / tezacaftor / ivacaftor compound (ETI) is approved
for pwCF aged 6 and older and at least one F508del mutation. ETI is widely considered
a life changer by most who use or prescribe it, to the point that there is now some
discussion in the CF community about changes in the strategy of care and consideration
on how the future framework of CF centers may be affected by long term ETI usage [
[1]
]. The achievements of ETI have indeed been so patent that CF drug development is now
largely focused towards treatments for pwCF ineligible for CFTR modulator therapies
[
[2]
].To read this article in full you will need to make a payment
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References
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Article info
Publication history
Published online: March 05, 2023
Accepted:
February 20,
2023
Received in revised form:
February 15,
2023
Received:
February 2,
2023
Publication stage
In Press Corrected ProofIdentification
Copyright
© 2023 European Cystic Fibrosis Society. Published by Elsevier B.V. All rights reserved.