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Letter to the Editor| Volume 21, ISSUE 6, P1080-1081, November 2022

Research letter: The impact of elexacaftor/tezacaftor/ivacaftor on adherence to nebulized maintenance therapies in people with cystic fibrosis

  • Jia Tong Song
    Affiliations
    Faculty of Medicine, University of British Columbia
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  • Sameer Desai
    Affiliations
    School of Population and Public Health, University of British Columbia, Vancouver, BC, Canada
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  • Alessandro N. Franciosi
    Affiliations
    Centre for Heart Lung Innovation, University of British Columbia and St. Paul's Hospital, Vancouver, BC, Canada

    Division of Respiratory Medicine, Department of Medicine, University of British Columbia, Vancouver, BC, Canada
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  • Renee V.E. Dagenais
    Affiliations
    Department of Pharmacy, St. Paul's Hospital, Vancouver, BC, Canada

    Adult Cystic Fibrosis Program, St. Paul's Hospital, Vancouver, BC, Canada
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  • Bradley S. Quon
    Correspondence
    Corresponding author at: #166 - 1081 Burrard Street. Centre for Heart Lung Innovation, University of British Columbia and St. Paul's Hospital, Vancouver, BC, Canada.
    Affiliations
    Centre for Heart Lung Innovation, University of British Columbia and St. Paul's Hospital, Vancouver, BC, Canada

    Division of Respiratory Medicine, Department of Medicine, University of British Columbia, Vancouver, BC, Canada
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Published:May 15, 2022DOI:https://doi.org/10.1016/j.jcf.2022.05.005
Research letter: The impact of elexacaftor/tezacaftor/ivacaftor on adherence to nebulized maintenance therapies in people with cystic fibrosis
Previous ArticleA case of Elexacaftor-Tezacaftor-Ivacaftor induced rash resolving without interruption of treatment
Next ArticleAvailability of CFTR modulators in countries of Eastern Europe: The reality in 2022

      Highlights

      • •
        Reducing treatment burden is a high priority for people living with CF.
      • •
        Standard of care involves the use of multiple nebulized therapies which are time consuming.
      • •
        Prescription refills for nebulized dornase alfa and hypertonic saline decreased in the first year post-ETI.
      • •
        Several ongoing studies are evaluating the safety of withdrawing nebulized therapies post-ETI.

      Keywords

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      References

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      Article info

      Publication history

      Published online: May 15, 2022
      Accepted: May 9, 2022
      Received in revised form: May 6, 2022
      Received: January 12, 2022

      Identification

      DOI: https://doi.org/10.1016/j.jcf.2022.05.005

      Copyright

      © 2022 European Cystic Fibrosis Society. Published by Elsevier B.V. All rights reserved.

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