Journal of Cystic Fibrosis
Volume 10, Supplement 2 , Pages S16-S23, June 2011

European cystic fibrosis bone mineralisation guidelines

  • Isabelle Sermet-Gaudelus

      Affiliations

    • Pôle de Pediatric Multidisciplinaire, Hôpital Necker, Université René Descartes, 75015 Paris, France
    • Corresponding Author InformationCorresponding authors: Isabelle Sermet-Gaudelus, Pôle de Pediatric Multidisciplinaire, Hôpital Necker, INSERM U 845, Université René Descartes, 149 rue de Sévres, 75015 Paris, France. Tel.: +33 1 44 49 48 87; fax: +33 1 44 38 17 50
    • ,
  • Maria Luisa Bianchi

      Affiliations

    • Bone Metabolism Unit, Istituto Auxologico Italiano IRCCS, 20145 Milano, Italy
    • ,
  • Michèle Garabédian

      Affiliations

    • Université René Descartes, 75015 Paris, France
    • ,
  • Robert M. Aris

      Affiliations

    • The School of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA
    • ,
  • Alison Morton

      Affiliations

    • Adult Cystic Fibrosis Centre, St James University Hospital, LS9 7TF Leeds, UK
    • ,
  • Dana S. Hardin

      Affiliations

    • Ohio State University, Nationwide Children's Hospital, Columbus, OH 43201, USA
    • ,
  • Sarah L. Elkin

      Affiliations

    • Department of Respiratory Medicine, St Mary's Hospital, W2 1NY London, UK
    • ,
  • Juliet E. Compston

      Affiliations

    • Department of Medicine, University of Cambridge, CB2 2QQ Cambridge, UK
    • ,
  • Steven P. Conway

      Affiliations

    • Adult Cystic Fibrosis Centre, St James University Hospital, LS9 7TF Leeds, UK
    • ,
  • Mireille Castanet

      Affiliations

    • Pôle de Pediatric Multidisciplinaire, Hôpital Necker, Université René Descartes, 75015 Paris, France
    • ,
  • Susan Wolfe

      Affiliations

    • Paediatric Cystic Fibrosis Centre, The Leeds Children's Hospital, LGI, LS1 3EX Leeds, UK
    • ,
  • Charles S. Haworth

      Affiliations

    • Adult Cystic Fibrosis Centre, Papworth Hospital, CB23 3RE Cambridge, UK
    • Corresponding Author InformationCharles Haworth, Adult Cystic Fibrosis Centre, Papworth Hospital, CB23 3RE Cambridge, UK. +44-1480-364122; fax 0044-1480-364330

Abstract 

Patients with cystic fibrosis (CF) are at risk of developing low bone mineral density (BMD) and fragility fractures. This paper presents consensus statements that summarise current knowledge of the epidemiology and pathophysiology of CF-related skeletal deficits and provides guidance on its assessment, prevention and treatment. The statements were validated using a modified Delphi methodology.

Keywords:  Cystic fibrosis , Dual Energy X-ray Absorptiometry (DXA) , Bone density , Fractures , Bisphosphonates , Calcium , Vitamin D , Puberty

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PII: S1569-1993(11)60004-0

doi:10.1016/S1569-1993(11)60004-0

Journal of Cystic Fibrosis
Volume 10, Supplement 2 , Pages S16-S23, June 2011

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