Patient-reported pain and impaired sleep quality in adult patients with cystic fibrosis☆
Received 12 May 2009; received in revised form 6 July 2009; accepted 14 July 2009.
Abstract
Background
Sleep impairment has been described in patients with cystic fibrosis (CF). Pain is a known cause of sleep disturbance and as pain is commonly reported in patients with CF, we sought to find an association between impaired sleep quality and pain.
Methods
Fifty adult CF patients completed surveys of pain and sleep quality. The results were analyzed with additional clinical data including age, sex, nutritional status, and lung function.
Results
Thirty-two patients (64%) reported recent pain and 33 patients (66%) reported abnormal sleep quality. The patients with pain report worse sleep quality than those without pain (p=0.006). There was a strong correlation between impaired sleep quality and pain (p<0.0001).
Conclusions
We found that pain and poor sleep quality are reported in a majority of adult CF patients and there is a strong correlation between the two. This will have important clinical implications in the evaluation and treatment of adult patients.
aDepartment of Medicine, Medical University of South Carolina, 96 Jonathan Lucas Street, Room 812-CSB, Charleston, SC 29425, United States
bDepartment of Pediatrics, Medical University of South Carolina, 96 Jonathan Lucas Street, Room 812-CSB, Charleston, SC 29425, United States
cDepartment of Biometry, Medical University of South Carolina, 96 Jonathan Lucas Street, Room 812-CSB, Charleston, SC 29425, United States
dDepartment of Respiratory Therapy, Medical University of South Carolina, 96 Jonathan Lucas Street, Room 812-CSB, Charleston, SC 29425, United States
Corresponding author. Medical University of South Carolina, 96 Jonathan Lucas Street, 812-CSB, Charleston, SC 29425, United States. Tel.: +1 843 792 9219; fax: +1 843 792 0732.
☆ Data have been presented at the North American Cystic Fibrosis Conference, Denver, CO, October 2006. Flume JE, Flume PA, Ahmed QA, Gray S, Lester MK, Wohlfeiler M, Wang W. Self reported sleep quality and pain in adult cystic fibrosis patients Pediatr Pulmonol 2006; S29: 404–405.
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