Journal of Cystic Fibrosis
Volume 8, Issue 5 , Pages 332-337 , September 2009

Pharmacokinetics and safety of tobramycin administered by the PARI eFlow® rapid nebulizer in cystic fibrosis

  • Dominique Hubert

      Affiliations

    • Service de Pneumologie, CRCM adultes, Hôpital Cochin, Assistance Publique des Hôpitaux de Paris, 75679 Paris Cedex 14, France
  • ,
  • Sylvie Leroy

      Affiliations

    • Clinique des Maladies Respiratoires, Hôpital Albert Calmette, CHRU de Lille, 59037 Lille Cedex, France
  • ,
  • Raphaële Nove-Josserand

      Affiliations

    • Adult Cystic Fibrosis Care Centre, Centre Hospitalier Lyon-Sud, Pierre-Bénite Cedex, France
  • ,
  • Marlène Murris-Espin

      Affiliations

    • Service de Pneumologie-Allergologie, CRCM adulte, Hôpital Larrey, CHRU de Toulouse, 31059 Toulouse Cedex 09, France
  • ,
  • Laurent Mely

      Affiliations

    • Centre de Ressources et Compétences pour la Mucoviscidose, Hôpital Renée Sabran, Hospices Civils de Lyon, France
  • ,
  • Stéphane Dominique

      Affiliations

    • Departement of Pneumology and CRCM mixte, Rouen University Hospital, 76031 Rouen Cedex, France
  • ,
  • Bertrand Delaisi

      Affiliations

    • Service de Pédiatrie, Hôpital Robert Debré, 75019 Paris, France
  • ,
  • Pearl Kho

      Affiliations

    • Novartis Horsham Research Centre, Horsham, West Sussex, UK
    • Corresponding Author InformationCorresponding author. Tel.: +44 1403 324658; fax: +44 1403 323060.
  • ,
  • John M Kovarik

      Affiliations

    • Novartis Pharma AG, 4002 Basel, Switzerland

Received 19 October 2008 ,Revised 25 June 2009 ,Accepted 1 July 2009.

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 Previous presentation of data. A summary of the results of this trial have been posted to the Novartis Clinical Trial Results Database. The data have been presented previously as a poster at the 30th European Cystic Fibrosis Conference (ECFC), 13–16 June 2007, Belek, Turkey.

PII: S1569-1993(09)00091-5

doi: 10.1016/j.jcf.2009.07.001

Journal of Cystic Fibrosis
Volume 8, Issue 5 , Pages 332-337 , September 2009