Journal of Cystic Fibrosis
Volume 8, Issue 4 , Pages 270-272 , July 2009

Very high-dose ergocalciferol is effective for correcting vitamin D deficiency in children and young adults with cystic fibrosis

  • Steven R. Boas

      Affiliations

    • Cystic Fibrosis Center of Chicago, 2401 Ravine Way, Suite 302, Glenview. Illinois 60025, United States
    • Department of Pediatrics, Evanston Hospital, 2650 Ridge Avenue, Evanston, Illinois 60201, United States
    • Corresponding Author InformationCorresponding authors. Department of Pediatrics, Evanston Hospital, 2650 Ridge Avenue, Evanston, Illinois 60201, United States. Tel.: +1 847 570 1438; fax: +1 847 570 0231.
    • ,
  • Joseph R. Hageman

      Affiliations

    • Department of Pediatrics, Evanston Hospital, 2650 Ridge Avenue, Evanston, Illinois 60201, United States
    • Corresponding Author InformationCorresponding authors. Department of Pediatrics, Evanston Hospital, 2650 Ridge Avenue, Evanston, Illinois 60201, United States. Tel.: +1 847 570 1438; fax: +1 847 570 0231.
    • ,
  • Louisa T. Ho

      Affiliations

    • Department of Medicine, Evanston Hospital, 2650 Ridge Avenue, Evanston, Illinois 60201, United States
    • ,
  • Marissa Liveris

      Affiliations

    • Cystic Fibrosis Center of Chicago, 2401 Ravine Way, Suite 302, Glenview. Illinois 60025, United States

Received 27 February 2009 ,Revised 17 March 2009 ,Accepted 3 April 2009.

References 

  1. Aris RM, Merkel PA, Bachrach LK, Borowitz DS, Boyle MP, Elkin SL, et al. Consensus statement: guide to bone health and disease in cystic fibrosis. J Clin Endo Met. 2005;90(3):1888–1896
  2. Chavasse RJ, Francis J, Balfour-Lynn I, Rosenthal M, Bush A. Serum vitamin D levels in children with cystic fibrosis. Pediatr Pulmonol. 2004;38:119–122
  3. American Academy of Pediatrics . In:  Kleinman RE editors. Pediatric Nutrition Handbook. Sixth edition. 2009;p. 464–465
  4. Boyle MP, Noschese ML, Watts SL, Davis ME, Stenner SE, Lechtzin N. Failure of high-dose ergocalciferol to correct vitamin D deficiency in adults with cystic fibrosis. Am J Respir Crit Care Med. 2005;172:212–217
  5. Wanner TJ, Lechtzin N, Davis ME, Watts S, Podliska MZ, Boyle MP, et al. Very high dose ergocalciferol is effective in correcting vitamin D deficiency in adults with cystic fibrosis. Pediatr Pulmnol. 2006;29:392
  6. Stephenson A, Brotherwood M, Robert P, Atenafu E, Corey M, Tullis E. Cholecalciferol significantly increases 25-hydroxy D concentrations in adults with cystic fibrosis. Am J Clin Nutr. 2007;85:1307–1311
  7. Mitchell R, Dorman JL, Schindler J, Steiber A. Measurement of and response to vitamin D concentrations in the cystic fibrosis population. Pediatr Pulmnol. 2007;30:383
  8. Prestridge AL, Hart M, Potter E, McColley SA. Successful individualized vitamin D repletion in pediatric patients with cystic fibrosis. Pediatr Pulmnol. 2007;30:395

PII: S1569-1993(09)00033-2

doi: 10.1016/j.jcf.2009.04.004

Journal of Cystic Fibrosis
Volume 8, Issue 4 , Pages 270-272 , July 2009

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