Journal of Cystic Fibrosis
Volume 5, Issue 4 , Pages 223-228 , December 2006

Predicting hypoxia in cystic fibrosis patients during exposure to high altitudes

  • Wolfgang Kamin

      Affiliations

    • Children's Hospital, Mainz University, 55101 Mainz, Germany
    • Corresponding Author InformationCorresponding author. Kinderklinik am Klinikum der Johannes-Gutenberg Universität Mainz, Abteilung Pädiatrische Pneumologie/Allergologie und Mukoviszidose, Langenbeckstr. 1, 55101 Mainz, Germany. Tel.: +49 6131 17 2602; fax: +49 6131 17 5597.
    • ,
  • Birthe Fleck

      Affiliations

    • Institute of Occupational, Social and Environmental Medicine, Mainz University, Germany
    • ,
  • Dirk-Mathias Rose

      Affiliations

    • Institute of Occupational, Social and Environmental Medicine, Mainz University, Germany
    • ,
  • Oliver Thews

      Affiliations

    • Institute of Physiology and Pathophysiology, Mainz University, Germany
    • ,
  • Wolfgang Thielen

      Affiliations

    • Children's Hospital, Mainz University, 55101 Mainz, Germany

Received 9 September 2005 ,Revised 15 February 2006 ,Accepted 9 March 2006.

References 

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  2. Dillard TA, Beninati WA, Berg BW. Air travel in patients with chronic obstructive pulmonary disease. Arch Intern Med. 1991;151:1793–1795
  3. Dillard TA, Rajagopal KR, Slivka WA, Berg BW, Mehm WJ, Lawless NP. Lung function during moderate hypobaric hypoxia in normal subjects and patients with chronic obstructive pulmonary disease. Aviat Space Environ Med. 1998;69:979–985
  4. Gong H, Tashkin DP, Lee EY, Simmons MS. Hypoxia-altitude simulation test. Am Rev Respir Dis. 1984;130:980–986
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  9. Rose DM, Fleck B, Thews O, Kamin WE. Blood gas-analysis in patients with cystic fibrosis to estimate hypoxemia during exposure to high altitude in a hypobaric chamber. Eur J Med Res. 2000;5:9–12
  10. Fischer R, Lang SM, Brückner K, Hoyer HX, Meyer S, Griese M, et al. Lung function in adults with cystic fibrosis at altitude: impact on air travel. Eur Respir J. 2005;25:718–724
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  15. Kamin WE, Fleck B, Rose D. Intensified physiotherapy improves fitness to fly in cystic fibrosis patients. Eur J Med Res. 2000;5:402–404
  16. Oades PJ, Buchdahl RM, Bush A. Prediction of hypoxaemia at high altitude in children with cystic fibrosis. BMJ. 1994;308:15–18
  17. ChiLem G, Perez Padilla R. Gas exchange at rest during simulated altitude in patients with chronic lung disease. Arch Med Res. 1998;29:57–62
  18. Vohra KP, Klocke RA. Detection and correction of hypoxemia associated with air travel. Am Rev Respir Dis. 1993;148:1215–1219

☆ The study was conducted jointly at the Children's Hospital, the Institute of Occupational, Social and Environmental Medicine and the Institute of Physiology and Pathophysiology of Mainz University, Germany.

PII: S1569-1993(06)00037-3

doi: 10.1016/j.jcf.2006.03.005

Journal of Cystic Fibrosis
Volume 5, Issue 4 , Pages 223-228 , December 2006

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