Journal of Cystic Fibrosis
Volume 5, Issue 4 , Pages 215-221 , December 2006

Paternity in men with cystic fibrosis: a retrospective survey in France

  • Ingrid Duguépéroux

      Affiliations

    • Service de Cytogénétique, Faculté de Médecine et des Sces de la Santé, UBO and CHU Morvan, 29388 Brest cedex 3, France
  • ,
  • Dominique Hubert

      Affiliations

    • CRCM Adultes, CH Cochin, AP-HP, 27, rue du Fbrg St Jacques, 75679 Paris cedex 14, France
  • ,
  • Stéphane Dominique

      Affiliations

    • CRCM Adultes, CHU C. Nicolle, 1, rue Germont, 76000 Rouen, France
  • ,
  • Gil Bellis

      Affiliations

    • Institut national d'Etudes Démographiques, 133, bd Davout, 75020 Paris, France
  • ,
  • Marc De Braekeleer

      Affiliations

    • Service de Cytogénétique, Faculté de Médecine et des Sces de la Santé, UBO and CHU Morvan, 29388 Brest cedex 3, France
    • Institut national d'Etudes Démographiques, 133, bd Davout, 75020 Paris, France
    • Corresponding Author InformationCorresponding author. Laboratoire de Cytogénétique, Faculté de Médecine et des Sciences de la Santé, Université de Bretagne Occidentale, 22, avenue Camille Desmoulins, CS 93837, F-29238 Brest cedex 3, France. Tel.: +33 2 98 01 64 76; fax: +33 2 98 01 81 89.
  • ,
  • Isabelle Durieu

      Affiliations

    • CRCM Adultes, CH Lyon-Sud, 69310 Pierre-Bénite, France

Received 23 September 2005 ,Revised 17 February 2006 ,Accepted 8 March 2006.

References 

  1. Feingold J. Rapport annuel de l'observatoire national de la mucoviscidose-année 1995. Paris: Association Française de Lutte contre la Mucoviscidose Publisher; 1996;
  2. Observatoire National de la Mucoviscidose . Rapport sur la situation de la mucoviscidose en France en 2002–2003. Paris: Vaincre la Mucoviscidose–Institut National d'Etudes Démographiques Publishers; 2005;
  3. Durieu I, Lepercq J, Rigot JM, Boggio D. Fertilité et reproduction. Rev Mal Respir. 2000;17:802–806
  4. Kaplan E, Shwachman H, Perlmutter AD, Rule A, Khaw KT, Holsclaw DS. Reproductive failure in males with cystic fibrosis. N Engl J Med. 1968;279:65–69
  5. Gottlieb C, Plöen L, Kvist U, Strandvik B. The fertility potential of male cystic fibrosis patients. Int J Androl. 1991;14:437–440
  6. Wong PYD. CFTR gene and male fertility. Mol Hum Reprod. 1998;4:107–110
  7. Gracey M, Campbell P, Noblett HR. Atretic vas deferens in cystic fibrosis. N Engl J Med. 1969;280:276
  8. Stern RC, Boat TF, Doershuk CF. Obstructive azoospermia as a diagnostic criterion for cystic fibrosis syndrome. Lancet. 1982;1:1401–1404
  9. Claustres M, Guittard C, Bozon D, Chevalier F, Verlingue C, Férec C, et al. Spectrum of CFTR mutation in cystic fibrosis and in congenital absence of vas deferens in France. Hum Mutat. 2000;16:143–156
  10. Amaral MD, Pacheco P, Beck S, Farinha CM, Pengue D, Nogueira P, et al. Cystic fibrosis patient with the 3272-26A>G splicing mutation have milder disease than F508del homozygotes: a large European study. J Med Genet. 2001;38:777–783
  11. Nove-Josserand R, Bey-Omar F, Rollet J, Lejeune H, Boggio D, Vital-Durand D, et al. Cystic fibrosis phenotype evaluation and paternity outcome in 50 males with congenital bilateral absence of vas deferens. Hum Reprod. 2001;16:2093–2097
  12. McCallum TJ, Milunsky JM, Cunningham DL, Harris MH, Maher TA, Oates RD. Fertility in men with cystic fibrosis: an update on current surgical practices and outcomes. Chest. 2000;118:1059–1062
  13. Dray X, Kanaan R, Bienvenu T, et al. Malnutrition in adults with cystic fibrosis. Eur J Clin Nutr. 2005;59:152–154
  14. Hubert D, Patrat C, Guibert J, Thiounn N, Bienvenu T, Viot G, et al. Results of assisted reproductive technique in men with cystic fibrosis. Hum Reprod. 2006 (January 23);[Electronc publication ahead of print]
  15. Badet F, Bellis G, De Braekeleer M, Nove Josserand R, Vital-Durand D, Durieu I, et al. Phenotype and genotype of French cystic fibrosis patients with long survival and follow-up. Eur J Intern Med. 2004;15:238–241
  16. Monnier A, Pennec S. Trois pour cent des moins de 21 ans sont orphelins en France. Popul Soc. 2003;396:1–4
  17. Bumbalo TS. Infertility in males with cystic fibrosis. Pediatrics. 1969;43:468
  18. Cabanel G, Voog R, Rambaud P. La mucoviscidose de l'adulte. Sem Hôp Paris. 1968;44:1203–1215
  19. Feigelson J, Pecau Y, Shwachman H. A propos d'une paternité chez un malade atteint de mucoviscidose. Etudes des fonctions génitales et de la filiation. Arch Fr Pediatr. 1969;26:937–944
  20. Feigelson J, Pecau Y. Mucoviscidose et paternité. Lyon Méd. 1971;226:839–840
  21. Blanck RR, Mendoza EM. Fertility in a man with cystic fibrosis. JAMA. 1976;235:1364
  22. Taussig LM, Lobeck CC, Di Sant'Agnese PA, Ackerman DR. Fertility in males with cystic fibrosis. N Engl J Med. 1972;287:586–589
  23. Barreto C, Marques Pinto L, Duarte A, Lavinha J, Ramsay M. A fertile male with cystic fibrosis: molecular genetic analysis. J Med Genet. 1991;28:420–421
  24. Dreyfus DH, Bethel R, Gelfand EW. Cystic fibrosis 3849+10 kbC→T mutation associated with severe pulmonary disease and male fertility. Am J Respir Crit Care Med. 1996;153:858–860
  25. Crowley S, Bush A. Cystic fibrosis: keeping it in the family. Pediatr Pulmonol. 2002;33:158–161
  26. Boyd JM, Mehta A, Murphy DJ. Fertility and pregnancy outcomes in men and women with cystic fibrosis in the United Kingdom. Hum Reprod. 2004;19:2238–2243
  27. De Braekeleer M, Bellis G, Rault G, Allard C, Millot M, Simard F. Disease knowledge in a high-risk population for cystic fibrosis. Patient Educ Couns. 2001;43:265–270
  28. Sawyer SM, Tully MAM, Dovey ME, Colin AA. Reproductive health in males with cystic fibrosis: knowledge, attitudes, and experiences of patients and parents. Pediatr Pulmonol. 1998;25:226–230
  29. Sawyer SM, Farrant B, Cerritelli B, Wilson J. A survey of sexual and reproductive health in men with cystic fibrosis: new challenges for adolescent and adult services. Thorax. 2005;60:230–326
  30. Duguépéroux I, Hubert D, Dominique S, Bellis G, De Braekeleer M, Durieu I. Paternity in men with cystic fibrosis: a retrospective study in France. Pediatr Pulmonol. 2004;S27:323–324

 Data presented at the 18th Annual North American Cystic Fibrosis Conference; St. Louis, October 14–17, 2004.

PII: S1569-1993(06)00036-1

doi: 10.1016/j.jcf.2006.03.004

Journal of Cystic Fibrosis
Volume 5, Issue 4 , Pages 215-221 , December 2006