« Previous
Next »
Journal of Cystic Fibrosis
Volume 5, Issue 2
, Pages 77-84
, May 2006
Fatty acids in blood and intestine following docosahexaenoic acid supplementation in adults with cystic fibrosis
References
- . Cystic fibrosis. Beyond gene to therapy. J Pediatr. 1992;120:337–349
- The relation between genotype and phenotype in cystic fibrosis—analysis of the most common mutation (ΔF508). N Engl J Med. 1990;323:1517–1522
- . Fatty acid abnormalities in cystic fibrosis. Pediatr Res. 1985;19:104–109
- . Supplemental calories improve essential fatty acid deficiency in cystic fibrosis patients. Pediatr Res. 1988;24:353–356
- . Increase of long chain omega-3 fatty acids in the major serum lipid classes of patients with cystic fibrosis. Ann Nutr Metab. 1992;36:304–312
- . Fatty acid pool size in plasma lipoprotein fractions of cystic fibrosis patients. Am J Clin Nutr. 1995;62:1268–1275
- . Biochemical assessment of the nutritional status of cystic fibrosis patients treated with pancreatic enzyme extracts. Am J Clin Nutr. 1998;67(5):912–918
- . Serum fatty acid profiles in cystic fibrosis patients and their parents. Lipids. 1994;29(8):569–575
- . Essential fatty acid status and fluidity of plasma phospholipids in cystic fibrosis infants. Am J Clin Nutr. 1991;54(6):1029–1035
- . Essential fatty acid deficiency in well nourished young cystic fibrosis patients. Eur J Pediatr. 1997;156(12):952–956
- . Polyunsaturated fatty acids and tocopherol levels in patients with cystic fibrosis. Ann N Y Acad Sci. 1972;203:237–247
- . Preparation of fatty acid methyl esters and dimethylacetals from lipids with boron fluoride methanol. J Lipid Res. 1964;5:600–608
- . Phosphatidylethanolamine methyltransferase: evidence for influence of diet fat on selectivity of substrate for methylation in rat brain synaptic plasma membrane. Biochim Biophys Acta. 1987;918:97–105
- . Effect of supplementing medium chain triglycerides with linoleic acid-rich monoglycerides on severely disturbed serum lipid fatty acid patterns in patients with cystic fibrosis. Ann Nutr Metab. 1985;29(4):239–245
- . Effect of administration of gamma-linolenic acid on the fatty acid composition of serum phospholipids and cholesteryl esters in patients with cystic fibrosis. Ann Nutr Metab. 1994;38(1):40–47
- . Liver function and morphology during long-term fatty acid supplementation in cystic fibrosis. Liver. 1994;14(1):32–36
- Fat malabsorption in cystic fibrosis patients receiving enzyme replacement therapy is due to impaired intestinal uptake of long-chain fatty acids. Am J Clin Nutr. 1999;69:127–134
- . The chloride channel blocker athracene 9-carboxylate inhibits fatty acid incorporation into phospholipid in cultured human airway epithelial cells. Biochem J. 1992;285:725–729
- . The ΔF508 mutation in the cystic fibrosis transmembrane conductance regulator alters control of essential fatty acid utilization in epithelial cells. J Nutr. 2000;130:2870–2875
- . Lignoceric acid is oxidized in the peroxisome: implications for the Zellweger cerebro-hepato-renal syndrome and adrenoleukodystrophy. Proc Natl Acad Sci U S A. 1984;81(13):4203–4207
- . Essential fatty acid deficiency in relation to genotype in patients with cystic fibrosis. J Pediatr. 2001;138:650–655
- . A membrane lipid imbalance plays a role in the phenotype expression of cystic fibrosis in CFTR mice. Proc Natl Acad Sci U S A. 1999;13995–14000
- . Essential fatty acid deficiency and predisposition to lung disease in cystic fibrosis. Acta Paediatr. 1996;85(12):1426–1432
- . Determination of sulfidopeptide leukotrienes in biological fluids by gas chromatography/mass spectrometry. Anal Chem. 1986;58:1098–1101
- . Variations in isomer distribution in commercially available conjugated linoleic acid. Fett-Lipid. 1999;101:277–282
- . Simultaneous analysis of low plasma levels of deuterium-labeled saturated and unsaturated fatty acids as t-butyldimethylsilyl esters. Lipids. 1986;21:247–251
- . Single-step separation of red blood cells. Granulocytes and mononuclear leukocytes on discontinuous density gradient of ficoll-hypaque. J Immunol Methods. 1974;5:249–252
- . Changes in erythrocyte membranes during preparation as expressed by ATPase activity. Biochim Biophys Acta. 1972;255:413–419
- . A simple method for the isolation and purification of total lipids from animal tissue. J Biol Chem. 1957;226:497–509
- . Improved separation of phospholipids in thin-layer chromatography. Lipids. 1980;15:61–62
- . Effect of linoleic acid intake on growth of infants with cystic fibrosis. Am J Clin Nutr. 1996;63(5):746–752
- . Paradoxical effects of essential fatty acid supplementation on lipid profiles and sweat electrolytes in cystic fibrosis. Br J Nutr. 1990;63(2):259–271
- . Prostanoid biosynthesis in patients with cystic fibrosis. Prostaglandins Leukot Essent Fatty Acids. 1996;55:419–425
- . Abnormal levels of prostaglandins and fatty acids in blood of children with cystic fibrosis. Lancet. 1978;2:236–238
- . Platelet function in patients with cystic fibrosis. Prog Lipid Res. 1986;25:305–307
- . The absorption and effect of dietary supplementation with omega-3 fatty acids on serum leukotriene B4 in patients with cystic fibrosis. Pediatr Pulmonol. 1994;18(4):211–217
- . Fatty acid composition of erythrocyte phospholipids from patients with cystic fibrosis. Clin Chim Acta. 1980;102:115–118
- . Essential fatty acid status in cystic fibrosis and the effects of safflower oil supplementation. Am J Clin Nutr. 1981;34:1–7
- . Pathological regulation of arachidonic release in cystic fibrosis: the putative basic defect. Proc Natl Acad Sci U S A. 1986;83:9202–9206
- Association of cystic fibrosis with abnormalities in fatty acid metabolism. N Engl J Med. 2004;350(6):560–569
- Characterization of LPS-induced lung inflammation in cftr+/− mice and the effect of docosahexaenoic acid. J Appl Physiol. 2002;92:2169–2176
- Beckles Willson N, Elliott TM, et al. Omega-3 fatty acids (from fish oil) for cystic fibrosis (Cochrane Review). In: The Cochrane Library, issue 1, 2003. Oxford: Update Software.
- . No indications for altered essential fatty acid metabolism in two murine models for cystic fibrosis. J Lipid Res. 2004;45:2277–2286
- . Molecular species compositions of lung and pancreas phospholipids in the cftrtml HGU/tml HGU cystic fibrosis mouse. Pediatr Res. 2003;53:447–454
☆ Grant Support: Financial support was obtained from Martek Biosciences Corporation, MTI MetaTech Inc. and National Science and Engineering Research Council (NSERC).
PII: S1569-1993(06)00022-1
doi: 10.1016/j.jcf.2006.01.004
© 2006 European Cystic Fibrosis Society. Published by Elsevier Inc. All rights reserved.
« Previous
Next »
Journal of Cystic Fibrosis
Volume 5, Issue 2
, Pages 77-84
, May 2006
