Journal of Cystic Fibrosis
Volume 2, Issue 1 , Pages 8-13 , March 2003

The 12-min walk test as an assessment criterion for lung transplantation in subjects with cystic fibrosis

  • Kristina Rüter

      Affiliations

    • Department of Pediatric Pneumology and Immunology, Charité, Humboldt University of Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
    • ,
  • Doris Staab

      Affiliations

    • Department of Pediatric Pneumology and Immunology, Charité, Humboldt University of Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
    • ,
  • Klaus Magdorf

      Affiliations

    • Department of Pediatric Pneumology and Immunology, Charité, Humboldt University of Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
    • ,
  • Susanne Bisson

      Affiliations

    • Institute for Statistics and Epidemiology, Benjamin Franklin Hospital, Free University of Berlin, Berlin, Germany
    • ,
  • Ulrich Wahn

      Affiliations

    • Department of Pediatric Pneumology and Immunology, Charité, Humboldt University of Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
    • ,
  • Karl Paul

      Affiliations

    • Department of Pediatric Pneumology and Immunology, Charité, Humboldt University of Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
    • Fachklinkik Sattledüne, Amrun, Germany
    • Corresponding Author InformationCorresponding author. Tel.: +49-4682-34300; fax: +49-4682-34708

References 

  1. Fitzsimmons SC. The changing epidemiology of cystic fibrosis. J Pediatr. 1992;122:1–8
  2. Boucek MM, Novick RJ, Bennett LE, Fiol B, Keck BM, Hosenpud JD. The registry of the International Society of Heart and Lung Transplantation: first official report—1997. J Heart Lung Transplant. 1997;16:1189–1206
  3. Arcasoy SM, Kotloff RM. Lung transplantation. New Engl J Med. 1999;14:1081–1089
  4. Hosenpud JD, Bennett LE, Keck BM, Edwards EB, Novick RJ. Effect of diagnosis on survival benefit of lung transplantation for end-stage lung disease. Lancet. 1998;35:24–27
  5. American Thoracic Society. International guidelines for the selection of lung transplant candidates. Am J Respir Crit Care Med. 1998;158:335–339
  6. Yankaskas JR, Mallory GB. Lung transplantation in cystic fibrosis: consensus conference statement. Chest. 1998;113:217–226
  7. McGavin CR, Gupta SP, McHardy GJR. Twelve-minute walking test for assessing disability in chronic bronchitis. Br Med J. 1976;1:822–823
  8. O'Reilly JF, Shaylor JM, Fromings KM, Harrison BDW. The use of the 12-minute walking test in assessing the effect of oral steroid therapy in patients with chronic airway obstruction. Br J Dis Chest. 1982;76:374–382
  9. Bellman MJ, Mittman C. Ventilatory muscle training improves exercise capacity in chronic obstructive pulmonary disease patients. Am Rev Respir Dis. 1980;121:273–280
  10. Bernstein ML, Despars JA, Singh NP, Avalos K, Stansbury DW, Light RW. Reanalysis of the 12 minute walk in patients with chronic obstructive pulmonary disease. Chest. 1994;105:163–167
  11. Kadikar A, Maurer J, Kesten S. The six-minute walk test: a guide to assessment for lung transplantation. J Heart Lung Transplant. 1997;16:313–319
  12. Knox AJ, Morrison JFJ, Muers MF. Reproducibility of walking test results in chronic obstructive airway disease. Thorax. 1988;43:388–392
  13. Nixon PA, Joswiak ML, Fricker FJ. A six-minute walk test for assessing exercise tolerance in severely ill children. J Pediatr. 1996;129:362–366
  14. Guyatt GH, Pugsley SO, Sullivan MJ, et al.  Effect of encouragement on walking test performance. Thorax. 1984;39:818–822
  15. Liou TG, Adler FR, Cahill BC, et al.  Survival effect of lung transplantation among patients with cystic fibrosis. J Am Med Assoc. 2001;286:2683–2689
  16. Kerem E, Reisman J, Corey M, Canny GJ, Levison H. Prediction of mortality in patients with cystic fibrosis. New Engl J Med. 1992;326:1187–1192
  17. Milla CE, Warbnick WJ. Risk of death in cystic fibrosis patients with severely compromised lung function. Chest. 1998;113:1230–1234
  18. Mak VH, Bugler JR, Roberts CM, Spiro SG. Effect of arterial oxygen desaturation on six-minute walk distance, perceived effort, and perceived breathlessness in patients with airflow limitation. Thorax. 1993;48:33–38

☆ Parts of this project were presented at the 23rd European Cystic Fibrosis Conference in The Hague, June 1999.

PII: S1569-1993(02)00145-5

doi: 10.1016/S1569-1993(02)00145-5

Journal of Cystic Fibrosis
Volume 2, Issue 1 , Pages 8-13 , March 2003

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