Journal of Cystic Fibrosis
Volume 2, Issue 1 , Pages 35-37, March 2003

Granulomatous diseases in a patient with cystic fibrosis

Department of Respiratory Medicine, E 11 South, Royal Prince Alfred Hospital, Missenden Road, Camperdown NSW 2050, Australia

Abstract 

We report the case of an adult with Crohn's disease and pulmonary sarcoidosis on the background of cystic fibrosis (CF). There is a recognized association between Crohn's colitis and CF, but cases of pulmonary sarcoidosis in CF are rare. There may be a pathogenic link between the two granulomatous disorders and CF with chronic immune stimulation leading to hyperimmunoglobulinemia, circulating immune complexes and subsequent granuloma formation.

Keywords: Cystic fibrosis, Crohn's disease, Sarcoidosis

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PII: S1569-1993(02)00140-6

doi:10.1016/S1569-1993(02)00140-6

Journal of Cystic Fibrosis
Volume 2, Issue 1 , Pages 35-37, March 2003

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